BPI East 2021
Date: September 20-23, 2021
Location: Boston Convention and Exhibition Center – Boston, MA
Manager, Manufacturing Process Optimization, Catalent
Date: Thursday, September 23, 2021
Session Track: Recovery & Purification track
Session Title: Evaluation of a Next Gen Downstream Approach to Improve Overall Manufacturing Process Intensity
Abstract: There are multiple methods to improve manufacturing production and efficiency for biologics, from cell line development through upstream and downstream processing. During this presentation, we evaluate whether next gen technology in downstream processing can further improve a manufacturing platform that leverages robust cell line development and an intensified cell culture process. We will outline a case study utilizing GPEx® and GPEx Boost cell line development technology and an intensified seed train combined with the chromatographic 3M Harvest filter to determine how the performance impacts overall manufacturing process intensity.