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Multidimensional Evaluation of mAb Degraded Under Light, Shear and Thermal Stress Conditions

Summary: This poster evaluates the degradation of a therapeutic mAb, Adalimumab, resulting from light, shear and thermal stress.  Degradation was evaluated using a combination of Sedimentation Velocity-Analytical Ultra-Centrifugation (SV-AUC), capillary Isoelectric Focusing (cIEF), and Liquid Chromatography coupled with Mass Spectrometry (LC-MS).

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