Multidimensional Evaluation of mAb Degraded Under Light, Shear and Thermal Stress Conditions
Summary: This poster evaluates the degradation of a therapeutic mAb, Adalimumab, resulting from light, shear and thermal stress. Degradation was evaluated using a combination of Sedimentation Velocity-Analytical Ultra-Centrifugation (SV-AUC), capillary Isoelectric Focusing (cIEF), and Liquid Chromatography coupled with Mass Spectrometry (LC-MS).