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GPEx Cell Line Development | Why Catalent?

Summary: Our GPEx® technology is based on a proprietary, pseudo-typed, high-performance vector that generates high-performance, highly stable, production cell lines in a wide variety of mammalian host cells, including; CHO-S, CHO-K1, CHO-DG44, HEK293, CAP and others. Virtually any cDNA (mAb and multigenic applications) can be packaged into the GPEx® retrovector and used to transduce your choice of mammalian cell line. To date, over 460 different mAb and mAb fusions and over 50 different recombinant proteins have been produced using the GPEx® system achieving large scale fed-batch production titers of over 7.0 g/L (CHO-S) and 2.5 g/L (HEK293).