Automating Cell-Based Assays Reducing Variability and Time to Results
Summary: Cell-based assays play a critical role in assessing potency for traditional biologics and advanced therapeutics. For all analytical methods, increasing accuracy and precision while decreasing variability are critical to optimizing a method. For a cell-based assay, due to their biologic nature, the variable material inputs provide a challenge. Therefore, other aspects of the analytical method will need to be assessed for improvement opportunities. Removing variability through automation can help increase assay robustness and ruggedness, as well as reduce time to results. In this presentation, we will discuss the development of cell-based potency assay on an automated platform.