Are Real-Time Gene Therapy Test Results Possible?
Summary: Along with the complexities of vaccine and viral-based gene therapy process development comes the need for analytical techniques that can help assess quality parameters, especially in real-time. LumaCyte’s Laser Force Cytology (LFC) instrument, Radiance®, provides rapid and accurate measurement of quality attributes such as viral titer and infectivity, helping to accelerate the development and production of these advanced therapies.
Traditional infectivity methods, including the TCID50 and viral plaque assays, can take days to weeks, with the results often suffering from subjectivity and requiring significant resources. Radiance® data is presented on rapid and low error adenovirus and baculovirus infectivity measurements as well as AAV transfection monitoring.